클로로 메틸 디메틸 실릴 클로라이드 (HC-CM2123)의 실란 세계 심층 분석 및 응용 전망의 다목적 플레이어

중합체 매트릭스에서의 분산 성을 향상시키기 위해 이산화탄소 및 탄소 나노 튜브의 표면 이식에 사용됩니다.

예 : 초-하이드로 공포증 코팅을위한 소수성 나노시오 (접촉각> 150 °)의 제조.

ⅳ. 안전 및 운영 규정

1. 위험

중요한 유기 실리콘 중간체로서, 클로로로 메틸 디메틸 클로로 실란은 독특한 반응성과 광범위한 응용 전망을 갖는다. 새로운 합성 방법과 응용 기술을 지속적으로 개발하고 기존의 과제를 극복함으로써, 유기 실리콘 화학 분야에서 더 큰 역할을하고 인류의 과학적 및 기술적 진보에 기여할 것입니다.

※ 인터넷의 사진, 침해 연락처가 삭제 된 경우.₂Si(CH₃)₂C1 + 2H₂O → HOCH₂Si(CH₃)₂OH + 2HCI

Electrophilicity: Chloromethyl (ClCH₂⁻) can be used as an alkylating agent and participate in electrophilic substitution reactions in organic synthesis.

Thermal stability: Stable at room temperature, but may decompose at high temperature (＞200℃) and release HCl gas.

Ⅱ. Synthesis Method

1. Laboratory synthesis

Raw materials: methyldichlorosilane ((CH₃)₂SiCl₂) and chloromethylating agent (such as methyl chloride, chloromethyl lithium).

Reaction Path:

step:

In tetrahydrofuran (THF), slowly add chloromethyl Grignard reagent (ClCH₂MgBr) dropwise at low temperature (-10°C).

After the reaction is completed, the product is hydrolyzed and distilled to purify it with a yield of about 60–70%.

2. Industrial preparation

Direct chloromethylation method:

Using methyldichlorosilane as raw material, in the presence of a catalyst (such as AlCl₃), it reacts with methyl chloride (CH₃Cl):

Process characteristics:

Reaction temperature: 80–100°C, pressure: normal pressure;

The catalyst can be recycled and the product can be purified by distillation (purity > 98%).

Ⅲ. Application fields

1. Organic silicon chemical intermediates

Silane coupling agent precursor:

Chloromethyl-containing siloxanes are prepared by hydrolysis or alcoholysis and are used for surface modification of glass fibers and fillers.

Example: Synthesis of chloropropyltrimethoxysilane ( ClCH₂CH₂CH₂Si(OCH₃)₃ ) to enhance the adhesion between rubber and metal.

2. Polymer material modification

Silicone rubber crosslinker:

As a bifunctional crosslinking agent, it participates in the vulcanization reaction of addition-type silicone rubber to improve heat resistance (＞250℃) and mechanical strength.

Case: Used for high temperature seals (automotive engines, aerospace) .

3. Electronic materials

Semiconductor packaging materials:

A silicon-containing resin with low dielectric constant (k

Photoresist additives:

Improve the adhesion and etching resistance of photoresist (applied in advanced processes below 7nm).

4. Pharmaceutical and pesticide synthesis

Silylation of drug molecules:

As a protecting group reagent, it is used for silylation protection of hydroxyl or amino groups (such as in the synthesis of antibiotic intermediates).

Pesticide synergist:

Modify the molecular structure of pesticides to enhance leaf permeability (such as pyrethroid pesticides).

Surface functionalizing agent:

Used for surface grafting of silicon dioxide and carbon nanotubes to improve their dispersibility in polymer matrices.

Example: Preparation of hydrophobic nano-SiO₂ (contact angle > 150°) for super-hydrophobic coating.

Ⅳ. Safety and operating regulations

1. Danger

Corrosive: It reacts with water to release HCl, which is highly irritating to the skin and eyes;

Flammability: low flash point, keep away from fire;

Environmental toxicity: Toxic to aquatic life, leakage into water bodies must be prevented.

2. Protective measures

Operation protection: Wear chemical-resistant gloves (nitrile/fluororubber), goggles and gas mask;

Storage conditions: Store in sealed containers in a dry, cool place (temperature

3. Emergency treatment

Leakage disposal: Use sand to absorb and collect in special containers, do not flush directly into the sewer;

Fire extinguishing method: Use dry powder or carbon dioxide fire extinguisher. Do not use direct water (to prevent splashing reaction).

Ⅴ. Future Trends

Green synthesis: Develop solvent-free catalytic processes (such as supercritical CO₂ media) to reduce the discharge of three wastes;

Functional expansion: design fluorine/amino-containing derivatives for use in biocompatible materials (such as medical catheter coatings);

High value-added applications: exploration of innovative applications in quantum dot displays and solid-state battery electrolytes.

VI. Summary and Outlook:

As an important organosilicon intermediate, chloromethyldimethylchlorosilane has unique reactivity and broad application prospects. By continuously developing new synthesis methods and application technologies and overcoming existing challenges, it will play a greater role in the field of organosilicon chemistry and contribute to the scientific and technological progress of mankind.

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